Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas
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چکیده
منابع مشابه
Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas
Solid pseudopapillary neoplasm (SPN) of the pancreas is a low-grade malignant neoplasm that accounts for ~5% of cystic pancreatic tumors and ~0.9‑2.7% of exocrine pancreatic tumors. The transcription profiling data (GSE43795) of 14 SPN and 6 control samples were downloaded from the Gene Expression Omnibus (GEO) database. Using the Limma package, Student's t‑tests were performed to identify diff...
متن کاملSolid Pseudopapillary Neoplasm of the Pancreas
SPN is a rare neoplasm that affects mainly young women. Despite this feature, SPN have been seen in both genders, multiple races, and at a wide range of ages. The genetic mechanism behind the development of SPN is distinct from the more lethal ductal carcinoma of the pancreas. This difference is reflected in the favorable outcome for patients with SPN. Surgery is typically curative in patents w...
متن کاملSolid Pseudopapillary Neoplasm of the Pancreas: Analysis of Seven Cases
BACKGROUND The purpose of this study was to describe as well as compare our surgical treatment experiences of solid pseudopapillary neoplasms (SPN) of the pancreas and to provide a review of the literature. METHODS A retrospective analysis of data from Vilnius University Hospital Santariskiu Klinikos (VUH SK) and of the literature, which was researched using Karger Publishers, Springer Scienc...
متن کاملThe Histological Origin of Solid-Pseudopapillary Neoplasm of the Pancreas
Solid-pseudopapillary neoplasm of the pancreas (SPNP), as a distinct tumor, often occurred in young female patients with both exocrine and endocrine differentiation. Our aim was to define the SPNP histogenesis and investigate the relationships between its histological origin and the sexual hormone receptors. 20 tumor samples were subjected to the analysis of immunohistologic staining patterns a...
متن کاملSilent Presentation of a Solid Pseudopapillary Neoplasm of the Pancreas
BACKGROUND Solid pseudopapillary neoplasm (SPN) is a rare tumor frequently found in the head or tail of the pancreas. It mainly presents in young women between the 2nd and 3rd decades of life. A predilection for African Americans and Asians has been observed and is rarely reported in children. Most patients are symptomatic, with abdominal pain as the most common presenting symptom. Clinical lab...
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2017
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2017.6800